(1) 산화그래핀을 이용한 백혈병 유발 돌연변이 유전자 신속 간편 진단법 개발

A simple PCR-based fluorometric system for detection of mutant fusion DNAs using a quencher-free fluorescent DNA probe and graphene oxide. (2015) Chem. Commun. 51, 6960-6963

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Fluorescence-based detection of single-nucleotide changes in RNA using graphene oxide and DNAzyme. (2015) Chem. Commun. 51, 5641-5644

(2) C형 간염 바이러스, 구제역 바이러스 등 바이러스 핵산중합효소 활성 간편 측정법 개발

A graphene oxide-based platform for the assay of RNA synthesis by RNA polymerase using a fluorescent peptide nucleic acid probe. (2013) Chem. Commun. 49, 9203-9205.

(3) 산화그래핀을 이용한 RNA 분리 및 핵산 상호작용의 원리 규명

Desorption of single-stranded nucleic acids from graphene oxide by disruption of hydrogen bonding. (2013) Analyst, 138, 1745–1749.

Mechanism of DNA Adsorption and Desorption on Graphene Oxide. (2014) Langmuir 30(42): 12587-12595.

(4) 기능성 올리고핵산 (DNAzyme , 펩티드핵산)을 이용한 점 돌연변이 유전자 정밀 진단법 개발

Detection of single base mutation in RNA using T4 RNA ligase-based nick-joining or DNAzyme-based nick-generation. (2011) Anal. Biochem. 414(2):303-305.

Site-selective Cleavage of RNA at Two Sites by Tandem DNAzyme and its Detection by Mass Spectrometry for Genotyping of SNP. (2013) Bull. Korean Chem. Soc. 34, 3543-3544.

Quantitative detection of single base mutation by combining PNA hybridization and MALDI-TOF mass analysis. (2013) Chem. Commun. 49, 3754-3756.